Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040072 | 0.85 | POLB (0.42) | MAPTRAB9AATMTDP1L3MBTL1 | |
| SCHEMBL9040067 | 0.85 | POLB (0.42) | MAPTRAB9AATMTDP1L3MBTL1 | |
| SCHEMBL9042267 | 0.85 | ATM (0.37) | MAPTATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9039615 | 0.85 | ATM (0.37) | MAPTATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9044938 | 0.82 | POLB (0.39) | — | |
| SCHEMBL9727986 | 0.81 | ALDH1A1 (0.43) | MAPTRAB9AATMTDP1ALDH1A1 | |
| SCHEMBL9205224 | 0.81 | ALDH1A1 (0.43) | MAPTRAB9AATMTDP1ALDH1A1 | |
| SCHEMBL336792 | 0.81 | ALDH1A1 (0.43) | MAPTRAB9AATMTDP1ALDH1A1 | |
| SCHEMBL337168 | 0.81 | ALDH1A1 (0.43) | MAPTRAB9AATMTDP1ALDH1A1 | |
| SCHEMBL9208976 | 0.81 | ALDH1A1 (0.43) | MAPTRAB9AATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |