Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143079 | 0.84 | CPT2 (0.47) | POLBKDM4ELMNANPC1SMN1; SMN2 | |
| SCHEMBL9039615 | 0.83 | ATM (0.37) | POLBNPC1SMN1; SMN2 | |
| SCHEMBL9042267 | 0.83 | ATM (0.37) | POLBNPC1SMN1; SMN2 | |
| SCHEMBL9044936 | 0.83 | POLB (0.41) | POLBCYP2D6CYP2C9GRIN2BKDM4E | |
| SCHEMBL9040751 | 0.82 | AOC3 (0.40) | — | |
| SCHEMBL7141674 | 0.79 | POLB (0.38) | POLBCYP2C9NPC1SMN1; SMN2 | |
| SCHEMBL9040067 | 0.79 | POLB (0.42) | POLBKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9040072 | 0.79 | POLB (0.42) | POLBKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7143386 | 0.76 | POLB (0.41) | POLBNPC1SMN1; SMN2 | |
| SCHEMBL7149001 | 0.75 | POLB (0.41) | POLBKDM4ELMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |