Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002302 | 0.75 | — | — | |
| SCHEMBL5222819 | 0.71 | HRH3 (0.32) | MEN1CYP2C9CYP2C19KMT2AHRH3 | |
| SCHEMBL3127470 | 0.71 | TSHR (0.42) | MAPTMEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL28724717 | 0.71 | — | — | |
| SCHEMBL5222817 | 0.71 | — | — | |
| SCHEMBL4094366 | 0.71 | HRH3 (0.40) | MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL14131257 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL3170042 | 0.70 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL528149 | 0.70 | LTA4H (0.41) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4917509 | 0.69 | TSHR (0.39) | MAPTPOLBMEN1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |