Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042659 | 0.90 | CCKBR (0.51) | CCKBRTP53POLBHPGD | |
| SCHEMBL9040702 | 0.89 | CCKBR (0.51) | CCKBRTP53MAPTALDH1A1KMT2A | |
| SCHEMBL9039757 | 0.88 | CCKBR (0.58) | CCKBRCCKARALDH1A1 | |
| SCHEMBL9040489 | 0.87 | CCKBR (0.47) | CCKBRCCKARMAPTCYP3A4TSHR | |
| SCHEMBL9038073 | 0.86 | CYP3A4 (0.53) | CCKBRTP53POLBCCKARMAPT | |
| SCHEMBL9039704 | 0.85 | CCKBR (0.60) | CCKBRCCKARMAPTCYP3A4TSHR | |
| SCHEMBL9042507 | 0.85 | CCKBR (0.59) | CCKBR | |
| SCHEMBL9040362 | 0.85 | CCKBR (0.52) | CCKBRCCKARMAPTALDH1A1HTT | |
| SCHEMBL9039625 | 0.84 | CCKBR (0.57) | CCKBRMAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL9042632 | 0.83 | CCKBR (0.51) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |