Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039719 | 0.89 | CCKBR (0.58) | CCKBRTSHRTP53MAPTALDH1A1 | |
| SCHEMBL9039747 | 0.88 | CCKBR (0.51) | CCKBRTSHRATMMAPK1SMN1; SMN2 | |
| SCHEMBL9042659 | 0.88 | CCKBR (0.51) | CCKBRTP53 | |
| SCHEMBL9042632 | 0.86 | CCKBR (0.51) | CCKBR | |
| SCHEMBL9039233 | 0.86 | CCKBR (0.61) | CCKBRMAPT | |
| SCHEMBL9048213 | 0.85 | CCKBR (0.51) | CCKBRTSHRATMMAPK1SMN1; SMN2 | |
| SCHEMBL9043246 | 0.85 | CCKBR (0.57) | CCKBRTSHRATMMAPK1SMN1; SMN2 | |
| SCHEMBL9038467 | 0.84 | CCKBR (0.56) | CCKBRTSHRMAPK1MAPTALDH1A1 | |
| SCHEMBL9039757 | 0.83 | CCKBR (0.58) | CCKBRALDH1A1 | |
| SCHEMBL9042507 | 0.83 | CCKBR (0.59) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |