Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038419 | 0.85 | ADRA2A (0.38) | PDE5AHPGDSMN1; SMN2NPC1MAPT | |
| SCHEMBL15616431 | 0.78 | PDE5A (0.50) | PDE5APTGS2HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL12963495 | 0.75 | ALDH1A1 (0.58) | PDE5AHPGDSMN1; SMN2MAPTKDM4E | |
| SCHEMBL7865948 | 0.75 | PDE5A (0.45) | PDE5APTGS2HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL7229585 | 0.74 | — | — | |
| SCHEMBL30096757 | 0.74 | — | — | |
| SCHEMBL20779896 | 0.74 | PDE5A (0.44) | PDE5APTGS2HSD11B1HPGDSMN1; SMN2 | |
| SCHEMBL22062343 | 0.73 | NAPRT (0.43) | SMN1; SMN2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL30548746 | 0.73 | PTGS2 (0.55) | PDE5APTGS2MAPK1ALDH1A1 | |
| SCHEMBL10350653 | 0.73 | PTGS2 (0.55) | PDE5APTGS2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273610-B1 | Herbicidal pyridinesulfonylureas | DU PONT (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5512535-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| US-5393733-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5209770-A | Containing pyrimidine ring | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5102444-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0334896-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989001937-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-09 | — | — | WO | disclosed |
| US-4774337-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0273610-A1 | Herbicidal pyridinesulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| WO-1988004297-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-16 | — | — | WO | disclosed |