Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755562 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9755601 | 0.77 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9039844 | 0.77 | AGTR1 (0.53) | AGTR1AGTR2RXRARXRB | |
| SCHEMBL9041914 | 0.76 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9043241 | 0.74 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL27403218 | 0.74 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL1123143 | 0.73 | RXRA (0.72) | NR4A2RXRARXRB | |
| SCHEMBL9653917 | 0.72 | AGTR2 (0.77) | AGTR1AGTR2 | |
| SCHEMBL9042348 | 0.72 | AGTR1 (0.48) | AGTR1AGTR2RXRARXRB | |
| SCHEMBL9532189 | 0.72 | RXRA (0.44) | NR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012002-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |