Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | QDPR | P09417 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270967 | 0.80 | HTR2C (0.52) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL10269098 | 0.74 | HTR2C (0.46) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL30431801 | 0.73 | HTR2C (0.66) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL4790435 | 0.73 | HTR2C (0.66) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL904011 | 0.73 | HTR2C (0.66) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| Hydrochloric Acid SCHEMBL9311920 | 0.72 | HTR2C (0.67) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL4791120 | 0.71 | SIGMAR1 (0.79) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL17366556 | 0.70 | HTR2C (0.57) | HTR2CSIGMAR1QDPRHTR6HTR7 | |
| SCHEMBL29914651 | 0.70 | HTR2C (0.66) | HTR2CSIGMAR1QDPR | |
| SCHEMBL21228136 | 0.70 | HTR2C (0.66) | HTR2CSIGMAR1QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |