Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | QDPR | P09417 | 3/20 | 0.43 |
| ▸ | LPL | P06858 | 3/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658693 | 0.86 | LIPG (0.43) | HTR2CSIGMAR1LPLLIPG | |
| Hydrochloric Acid SCHEMBL29407724 | 0.85 | LIPG (0.42) | HTR2CSIGMAR1LPLLIPG | |
| Hydrochloric Acid SCHEMBL28933184 | 0.85 | LIPG (0.42) | HTR2CSIGMAR1LPLLIPG | |
| SCHEMBL15721865 | 0.85 | LPL (0.50) | HTR2CSIGMAR1QDPRLPLLIPG | |
| SCHEMBL10269098 | 0.83 | HTR2C (0.46) | HTR2CSIGMAR1QDPRHTR7HTR6 | |
| SCHEMBL904008 | 0.80 | HTR2C (0.54) | HTR2CSIGMAR1QDPRHTR7HTR6 | |
| SCHEMBL30919843 | 0.80 | P2RX7 (0.47) | LPLLIPG | |
| SCHEMBL31334233 | 0.78 | LIPG (0.43) | LPLLIPG | |
| SCHEMBL23484478 | 0.77 | MAPK1 (0.50) | LPLLIPG | |
| SCHEMBL806784 | 0.76 | LIPG (0.60) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |