Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16082283 | 0.86 | GBA1 (0.53) | GBA1 | |
| SCHEMBL6641841 | 0.82 | IRAK4 (0.56) | GBA1 | |
| SCHEMBL27504590 | 0.81 | PDE5A (0.58) | — | |
| SCHEMBL6641030 | 0.80 | GBA1 (0.45) | GBA1 | |
| SCHEMBL6368146 | 0.80 | GRM1 (0.55) | GBA1 | |
| SCHEMBL16082203 | 0.79 | ABCG2 (0.58) | — | |
| SCHEMBL31151143 | 0.79 | DRD2 (0.57) | — | |
| SCHEMBL17652208 | 0.78 | IRAK4 (0.68) | — | |
| SCHEMBL16082245 | 0.78 | GBA1 (0.45) | GBA1 | |
| SCHEMBL6639888 | 0.77 | HPGDS (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602851-B1 | Quinazoline derivatives | ZENECA LTD (GB) | 1996-10-09 | — | — | EP | claimed |
| EP-0602851-B1 | Quinazoline derivatives | ZENECA LTD (GB) | 1996-10-09 | — | — | EP | disclosed |