Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19680488 | 0.93 | MEN1 (0.39) | GBA1MEN1KMT2ATHRBHTT | |
| SCHEMBL15299847 | 0.93 | GBA1 (0.37) | GBA1ALDH1A1TSHREPHX2 | |
| SCHEMBL15299866 | 0.93 | GBA1 (0.37) | GBA1ALDH1A1TSHREPHX2 | |
| SCHEMBL6726712 | 0.88 | GBA1 (0.36) | GBA1ALDH1A1EPHX2 | |
| SCHEMBL27521048 | 0.88 | GBA1 (0.36) | GBA1ALDH1A1EPHX2 | |
| SCHEMBL19288472 | 0.82 | NAAA (0.48) | MEN1KMT2AEPHX2 | |
| SCHEMBL9039433 | 0.82 | USP2 (0.36) | GBA1HTT | |
| SCHEMBL9039043 | 0.81 | MEN1 (0.35) | GBA1MEN1KMT2ATHRBHTT | |
| SCHEMBL4043902 | 0.81 | GBA1 (0.34) | GBA1EPHX2 | |
| SCHEMBL1232453 | 0.80 | ALDH1A1 (0.32) | GBA1ALDH1A1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | claimed |
| US-5145893-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | claimed |
| US-5574162-A | CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| US-5442071-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| US-5359069-A | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5286865-A | Contain reactive functional group which can be chemically attached to selected polymer substrates | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5145893-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |