Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040386 | 0.87 | LMNA (0.47) | LMNAMAPTALDH1A1KMT2ATRIM24 | |
| SCHEMBL7366622 | 0.82 | ALDH1A1 (0.44) | NFE2L2RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL4993422 | 0.81 | KMT2A (0.55) | RAB9ALMNAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL209651 | 0.79 | TRIM24 (0.52) | NFE2L2RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL29953915 | 0.79 | TRIM24 (0.52) | NFE2L2RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL7371098 | 0.77 | LMNA (0.47) | LMNAALDH1A1KMT2ATRIM24TRIM33 | |
| SCHEMBL3216908 | 0.77 | KMT2A (0.55) | RAB9ALMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL5878669 | 0.77 | KDM4E (0.49) | RAB9ALMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL4051215 | 0.77 | DYRK1A (0.55) | NFE2L2DYRK1ACLK4ALDH1A1ERN1 | |
| SCHEMBL7374241 | 0.75 | TDP1 (0.59) | RAB9ALMNAKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312243-B1 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LTD (GB) | 1996-08-07 | — | — | EP | disclosed |
| US-5198444-A | Methyl α-(2-substituted)pyrid-3-yl-β-methoxyacrylates, compositions containing them and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5158954-A | For agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-27 | — | — | US | disclosed |
| US-5008276-A | Plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |
| EP-0312243-A2 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |