Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9344800 | 0.99 | TOP2A (0.55) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9041557 | 0.87 | ALDH1A1 (0.42) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL28394940 | 0.85 | KDM4E (0.61) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9040954 | 0.85 | TOP2A (0.55) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL6217878 | 0.84 | ALDH1A1 (0.53) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9177373 | 0.82 | TOP2A (0.52) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9734112 | 0.81 | TOP2A (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9779879 | 0.80 | TOP2A (0.55) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9671100 | 0.80 | TOP2A (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8616936 | 0.80 | ALDH1A1 (0.66) | TOP2ATOP2BKCNH2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481274-B1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1996-10-23 | — | — | EP | claimed |
| US-5202337-A | Antibacterial agent, feed additive | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | claimed |
| EP-0481274-A1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-04-22 | — | — | EP | claimed |