Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040404 | 0.86 | MAPK14 (0.43) | ADORA1MAPK14LMNAADORA2BKDM4E | |
| SCHEMBL9040396 | 0.76 | ADORA2A (0.49) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9018998 | 0.74 | ADORA2B (0.48) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9037705 | 0.73 | ADORA2A (0.47) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9039673 | 0.73 | ADORA2A (0.47) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9039329 | 0.73 | ADORA2A (0.47) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9039691 | 0.73 | ADORA2A (0.43) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9041274 | 0.72 | ADORA2A (0.43) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9038553 | 0.72 | ADORA2A (0.43) | ADORA1ADORA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9040030 | 0.70 | ADORA2A (0.43) | LMNAADORA2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |