Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040840 | 0.86 | ADORA1 (0.42) | MAPK14ADORA1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL9019089 | 0.74 | ADORA2B (0.44) | ADORA1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL9038499 | 0.73 | ADORA2A (0.43) | ADORA1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL9039524 | 0.68 | ADORA3 (0.50) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL9038196 | 0.67 | ADORA2A (0.45) | ADORA1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL9233810 | 0.67 | SMN1; SMN2 (0.54) | MAPK14HPGDHTTNPSR1LMNA | |
| SCHEMBL9037887 | 0.67 | PDE4B (0.45) | ADORA1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL555828 | 0.65 | ADORA1 (0.63) | ADORA1ADORA2AHTTADORA3ADORA2B | |
| SCHEMBL555093 | 0.65 | ALDH1A1 (0.65) | ADORA1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9040396 | 0.65 | ADORA2A (0.49) | ADORA1ADORA2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |