Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057254 | 0.88 | MMP3 (0.38) | MMP3 | |
| SCHEMBL9040880 | 0.88 | ALOX5 (0.33) | F10PRSS1 | |
| SCHEMBL9042418 | 0.88 | KDM4E (0.36) | — | |
| SCHEMBL9039223 | 0.86 | AGTR1 (0.49) | — | |
| SCHEMBL9043141 | 0.85 | SCN9A (0.41) | F10PRSS1SCN9A | |
| SCHEMBL9043397 | 0.82 | IDO1 (0.37) | — | |
| SCHEMBL9041292 | 0.81 | AGTR1 (0.35) | — | |
| SCHEMBL9058030 | 0.80 | SCN9A (0.42) | F10PRSS1SCN9AMMP3 | |
| SCHEMBL9055956 | 0.79 | PTPN1 (0.42) | — | |
| SCHEMBL9042483 | 0.78 | SCN9A (0.42) | F10PRSS1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |