SCHEMBL9040898

SCHEMBL9040898

CCOC(=O)CN1C(=O)C(NC(=O)Nc2cccc(C)c2)C(c2ccccc2)=Cc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 9/20 0.50
CCKAR P32238 4/20 0.48
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9042321 0.83 CCKBR (0.58) CCKBR
SCHEMBL9040407 0.80 CCKBR (0.44) CCKBRCCKAR
SCHEMBL9039602 0.79 CCKBR (0.57) CCKBRCCKARCYP3A4MAPTTSHR
SCHEMBL8533593 0.77 CCKBR (0.82) CCKBRCCKARCYP3A4MAPTTSHR
SCHEMBL8773990 0.77 CCKBR (0.82) CCKBRCCKARCYP3A4MAPTTSHR
SCHEMBL7467452 0.76 CCKBR (0.71) CCKBRCCKAR
SCHEMBL7613922 0.72 ALDH1A1 (0.48) CCKBRCCKAR
SCHEMBL7613913 0.72 ALDH1A1 (0.48) CCKBRCCKAR
SCHEMBL9040039 0.72 CCKBR (0.61) CCKBRCCKAR
Trifluoroacetic Acid SCHEMBL9040468 0.72 CCKBR (0.44) CCKBRCCKARMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703222-A1 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-03-27 EP disclosed