SCHEMBL9040407

SCHEMBL9040407

CCOC(=O)CN1C(=O)C(NC(=O)OC(C)(C)C)C(c2ccccc2)=Cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 6/20 0.44
CCKAR P32238 2/20 0.44
GAA P10253 2/20 0.38
NPSR1 Q6W5P4 1/20 0.37
SCN9A Q15858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9040876 0.81 SCN9A (0.44) CCKBRCCKARSCN9A
SCHEMBL9040898 0.80 CCKBR (0.50) CCKBRCCKAR
SCHEMBL11118972 0.79 NFKB1 (0.46) CCKBRCCKARGAANPSR1
Trifluoroacetic Acid SCHEMBL9040468 0.77 CCKBR (0.44) CCKBRCCKARGAANPSR1
SCHEMBL8585550 0.75 CCKBR (0.71) CCKBRCCKARSCN9A
SCHEMBL8585545 0.75 CCKBR (0.71) CCKBRCCKARSCN9A
SCHEMBL7421691 0.75 CCKBR (0.51) CCKBR
SCHEMBL9040545 0.74 CCKBR (0.45) CCKBRGAA
SCHEMBL7568437 0.73 CCKBR (0.46) CCKBRCCKAR
SCHEMBL10499355 0.73 CCKBR (0.46) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703222-A1 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-03-27 EP disclosed