Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | LGMN | Q99538 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 9/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253253 | 0.79 | GAA (0.49) | LGMNBPTFALDH1A1MAPTALOX15 | |
| Dimethylamine SCHEMBL9041971 | 0.79 | SMN1; SMN2 (0.46) | IP6K1LGMNSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27760675 | 0.77 | BPTF (0.40) | LGMNBPTFCTSKCTSCALDH1A1 | |
| SCHEMBL6222765 | 0.74 | IP6K1 (0.51) | IP6K1LGMNL3MBTL1 | |
| SCHEMBL9042190 | 0.74 | KDM4E (0.55) | IP6K1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL2463468 | 0.73 | CTSK (0.41) | IP6K1CTSKCTSCALDH1A1MAPT | |
| SCHEMBL2463471 | 0.73 | CTSK (0.41) | IP6K1CTSKCTSC | |
| SCHEMBL22652219 | 0.71 | GAA (0.35) | IP6K1LGMNCTSKCTSCALDH1A1 | |
| SCHEMBL9041965 | 0.70 | BPTF (0.42) | BPTFALDH1A1NOTUMKDM4EHSD17B10 | |
| SCHEMBL12092567 | 0.69 | NOTUM (0.46) | BPTFALDH1A1MAPTNOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |