Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 16/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 15/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.47 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | LGMN | Q99538 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310306 | 0.81 | L3MBTL3 (0.55) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL9042190 | 0.78 | KDM4E (0.55) | IP6K1 | |
| SCHEMBL2462397 | 0.78 | IP6K1 (0.43) | IP6K1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL3532834 | 0.78 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL10290706 | 0.77 | L3MBTL1 (0.60) | IP6K1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL310165 | 0.77 | L3MBTL1 (0.60) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL310733 | 0.77 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| Dimethylamine SCHEMBL9041971 | 0.76 | SMN1; SMN2 (0.46) | IP6K1LGMN | |
| SCHEMBL13559445 | 0.76 | L3MBTL3 (0.68) | IP6K1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL309496 | 0.76 | L3MBTL1 (0.51) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501799-A1 | COMPOUNDS USEFUL IN PREPARING CAMPTOTHECIN DERIVATIVES | Pharmacia Corporation (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003089413-A1 | PHARMACIA CORPORATION | PHARMACIA CORPORATION (US) | 2003-10-30 | — | — | WO | claimed |