Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | LGMN | Q99538 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774941 | 0.82 | GAA (0.51) | SMN1; SMN2IP6K1LGMNGAAAVPR2 | |
| SCHEMBL9041963 | 0.79 | IP6K1 (0.40) | SMN1; SMN2IP6K1LGMNALDH1A1KDM4E | |
| SCHEMBL6222765 | 0.76 | IP6K1 (0.51) | IP6K1LGMN | |
| SCHEMBL9042190 | 0.76 | KDM4E (0.55) | IP6K1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL17774916 | 0.75 | GAA (0.62) | SMN1; SMN2IP6K1GAAAVPR2ALDH1A1 | |
| SCHEMBL7674084 | 0.74 | IP6K1 (0.54) | SMN1; SMN2IP6K1LGMNGAANPC1 | |
| SCHEMBL10209559 | 0.71 | ALDH1A1 (0.46) | LGMNGAAALDH1A1KDM4EMAPT | |
| SCHEMBL12862353 | 0.71 | ALDH1A1 (0.46) | LGMNGAAALDH1A1KDM4EMAPT | |
| SCHEMBL15096670 | 0.71 | PDK2 (0.42) | LGMNGAAAVPR2NPC1RAB9A | |
| SCHEMBL13558242 | 0.69 | USP2 (0.55) | SMN1; SMN2GAANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |