Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041391 | 1.00 | MAOB (0.36) | MAOBPTPRCPTPN1KMT2AMAOA | |
| SCHEMBL9041399 | 1.00 | MAOB (0.36) | MAOBPTPRCPTPN1KMT2AMAOA | |
| SCHEMBL9043794 | 0.92 | PTPRC (0.43) | MAOBPTPRCPTPN1KMT2AMAOA | |
| SCHEMBL9041671 | 0.92 | PTPRC (0.43) | MAOBPTPRCPTPN1KMT2AMAOA | |
| SCHEMBL9042817 | 0.82 | L3MBTL1 (0.40) | MAOBPTPRCPTPN1MAOATDP1 | |
| SCHEMBL9042899 | 0.80 | MAOB (0.38) | MAOBPTPRCPTPN1MAOATDP1 | |
| SCHEMBL9041795 | 0.78 | MAOB (0.36) | MAOBPTPRCPTPN1MAOATDP1 | |
| SCHEMBL9043779 | 0.74 | ALDH1A1 (0.33) | MAOBKMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL9042766 | 0.73 | PTPRC (0.47) | MAOBPTPRCPTPN1MAOATDP1 | |
| SCHEMBL9043317 | 0.72 | HIF1A (0.40) | MAOBTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |