Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042022 | 0.91 | PTPRC (0.37) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9042817 | 0.87 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1MAPTLMNAHTT | |
| SCHEMBL9044253 | 0.78 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9042766 | 0.78 | PTPRC (0.47) | L3MBTL1MAPTLMNAHTTRAB9A | |
| SCHEMBL9042899 | 0.78 | MAOB (0.38) | ALDH1A1L3MBTL1MAPTLMNANPC1 | |
| SCHEMBL9043309 | 0.77 | HIF1A (0.40) | ALDH1A1L3MBTL1MAPTLMNARAB9A | |
| SCHEMBL9043317 | 0.77 | HIF1A (0.40) | ALDH1A1L3MBTL1MAPTLMNARAB9A | |
| SCHEMBL9042937 | 0.75 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL9041399 | 0.74 | MAOB (0.36) | ALDH1A1L3MBTL1KMT2AHTTKDM4E | |
| SCHEMBL9042085 | 0.74 | MAOB (0.36) | ALDH1A1L3MBTL1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |