Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040100 | 0.86 | GABRB2 (0.35) | ARACHE | |
| SCHEMBL9041344 | 0.79 | AR (0.33) | AR | |
| SCHEMBL9033966 | 0.79 | ALDH1A1 (0.36) | ARKMT2AMEN1 | |
| SCHEMBL9043599 | 0.78 | LMNA (0.38) | AROPRM1OPRK1 | |
| SCHEMBL9043916 | 0.73 | POLB (0.35) | AROPRM1OPRK1 | |
| SCHEMBL15561086 | 0.73 | JAK2 (0.50) | ARKMT2AMEN1 | |
| SCHEMBL9043421 | 0.73 | KDM4E (0.36) | ARKMT2A | |
| SCHEMBL15561088 | 0.70 | TSHR (0.35) | AR | |
| SCHEMBL15561129 | 0.68 | KDM4E (0.40) | ARKMT2AMEN1 | |
| SCHEMBL9041668 | 0.68 | TSHR (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-B1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |