Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044919 | 0.85 | L3MBTL1 (0.40) | L3MBTL1ITGB3ITGA2BMAPT | |
| SCHEMBL9042223 | 0.79 | FFAR1 (0.39) | L3MBTL1 | |
| SCHEMBL192406 | 0.78 | CTSS (0.54) | SYKCTSSCTSKATM | |
| SCHEMBL192405 | 0.78 | CTSS (0.54) | SYKCTSSCTSKATM | |
| SCHEMBL9042766 | 0.77 | PTPRC (0.47) | L3MBTL1MAPT | |
| SCHEMBL9042817 | 0.75 | L3MBTL1 (0.40) | L3MBTL1MAPT | |
| SCHEMBL23837230 | 0.75 | CTSS (0.60) | SYKCTSSCTSKBACE1ATM | |
| SCHEMBL17724519 | 0.75 | CTSS (0.60) | SYKCTSSCTSKBACE1ATM | |
| SCHEMBL4689229 | 0.74 | CTSS (0.53) | SYKCTSSCTSKATMMAPT | |
| SCHEMBL4689227 | 0.74 | CTSS (0.53) | SYKCTSSCTSKATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |