Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042223 | 0.90 | FFAR1 (0.39) | L3MBTL1FFAR1PRKCAPRKCDLMNA | |
| SCHEMBL9042145 | 0.85 | L3MBTL1 (0.41) | L3MBTL1MAPTITGB3ITGA2B | |
| SCHEMBL9042766 | 0.81 | PTPRC (0.47) | L3MBTL1FFAR1MAPTLMNARAB9A | |
| SCHEMBL9042817 | 0.77 | L3MBTL1 (0.40) | L3MBTL1MAPTLMNARAB9A | |
| SCHEMBL9043071 | 0.76 | PPARA (0.34) | L3MBTL1FFAR1PTGER4PTGER3PTGER2 | |
| SCHEMBL9044383 | 0.76 | L3MBTL1 (0.39) | L3MBTL1FFAR1MAPTLMNARAB9A | |
| SCHEMBL9044386 | 0.76 | L3MBTL1 (0.39) | L3MBTL1FFAR1MAPTLMNARAB9A | |
| SCHEMBL9044253 | 0.75 | ALDH1A1 (0.38) | L3MBTL1PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL9042165 | 0.73 | PTPRC (0.49) | L3MBTL1PRKCAPRKCDMAPTLMNA | |
| SCHEMBL9043317 | 0.73 | HIF1A (0.40) | L3MBTL1MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |