Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.64 |
| ▸ | BCHE | P06276 | 10/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.49 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040699 | 0.99 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2ATSHR | |
| Water SCHEMBL9830096 | 0.79 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2ATSHR | |
| SCHEMBL9870090 | 0.79 | ACHE (0.61) | ACHEBCHEGRIN1GRIN2ATSHR | |
| SCHEMBL9039832 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ATSHR | |
| SCHEMBL9870494 | 0.78 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ATSHR | |
| SCHEMBL9739247 | 0.76 | ACHE (0.67) | ACHEBCHEGRIN1GRIN2ATSHR | |
| Water SCHEMBL9040201 | 0.75 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2ATSHR | |
| SCHEMBL9738570 | 0.75 | ACHE (0.58) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| Water SCHEMBL9043013 | 0.74 | ACHE (0.57) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9738826 | 0.74 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |
| EP-0430114-B1 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0430114-A2 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4994452-A | Memory disfunction | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-02-19 | — | — | US | disclosed |