Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.68 |
| ▸ | BCHE | P06276 | 11/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653196 | 0.82 | ACHE (0.70) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL9583623 | 0.82 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL9739247 | 0.81 | ACHE (0.67) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| Water SCHEMBL9040201 | 0.80 | ACHE (0.65) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL9749735 | 0.80 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL28984974 | 0.80 | ACHE (0.66) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| Water SCHEMBL9830096 | 0.79 | ACHE (0.65) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL10653394 | 0.79 | ACHE (0.64) | ACHEGRIN1GRIN2ABCHEGRIN2B | |
| SCHEMBL9583526 | 0.79 | ACHE (1.00) | ACHEGRIN1GRIN2ABCHEKDM4E | |
| SCHEMBL9042257 | 0.78 | ACHE (0.64) | ACHEGRIN1GRIN2ABCHEGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102495-B | 1,2,3, 4-Tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-116102495-A | 1,2,3, 4-tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2023-05-12 | — | — | CN | disclosed |
| EP-0430114-B1 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5202440-A | Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines | PFIZER INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0430114-A2 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4994452-A | Memory disfunction | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0311303-A2 | 4-aminopyridine derivatives | PFIZER INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |