Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.67 |
| ▸ | BCHE | P06276 | 9/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.54 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.44 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.44 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9040201 | 0.99 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| Water SCHEMBL9830096 | 0.88 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9738826 | 0.86 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| Water SCHEMBL9039788 | 0.86 | ACHE (0.59) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9738570 | 0.81 | ACHE (0.58) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9039832 | 0.81 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9870090 | 0.81 | ACHE (0.61) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| Water SCHEMBL9043013 | 0.80 | ACHE (0.57) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9870494 | 0.80 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACACNB4 | |
| SCHEMBL9042257 | 0.76 | ACHE (0.64) | ACHEBCHEGRIN1GRIN2ACACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |