Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904255 | 0.88 | CETP (0.52) | CETPPTGDR2TBXA2RPTGDRTDP1 | |
| SCHEMBL904261 | 0.81 | CETP (0.49) | CETPTLR2TLR1PTGDR2TBXA2R | |
| SCHEMBL11414229 | 0.77 | NOX1 (0.41) | CETPTLR2TLR1PTGDR2TDP1 | |
| SCHEMBL531379 | 0.77 | CETP (0.63) | CETP | |
| SCHEMBL904257 | 0.77 | CETP (0.45) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL2501697 | 0.77 | PTGDR2 (0.71) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL132381 | 0.76 | CETP (0.44) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL148769 | 0.76 | PTGDR2 (0.61) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL10035026 | 0.75 | ALDH1A1 (0.44) | CETPTLR2TLR1 | |
| SCHEMBL30780913 | 0.75 | TDP1 (0.58) | TTRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |