Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650235 | 0.82 | RORC (0.46) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6650250 | 0.81 | CTSV (0.52) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6651351 | 0.81 | LMNA (0.52) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL904263 | 0.81 | CETP (0.52) | CETPTDP1TBXA2RPTGDRPTGDR2 | |
| SCHEMBL29786763 | 0.80 | CFTR (0.48) | CETPCFTRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6649874 | 0.80 | KCNMA1 (0.55) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10110458 | 0.79 | CETP (0.58) | CETPCFTR | |
| SCHEMBL904252 | 0.79 | CFTR (0.47) | CETPCFTRHTTMAPTTBXA2R | |
| SCHEMBL9068677 | 0.78 | ALDH1A1 (0.54) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12114840 | 0.78 | RORC (0.54) | PKMHTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |