Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | COMT | P21964 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043085 | 0.80 | KDM4E (0.68) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL9044486 | 0.80 | KDM4E (0.71) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL31661039 | 0.76 | NPC1 (0.50) | KDM4EALDH1A1TP53SMN1; SMN2HPGD | |
| SCHEMBL2244254 | 0.76 | KDM4E (1.00) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL10875824 | 0.73 | AURKA (0.47) | KDM4EALDH1A1TP53SMN1; SMN2HPGD | |
| SCHEMBL6125983 | 0.72 | DGAT1 (0.53) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4057633 | 0.71 | MEN1 (0.53) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL24075063 | 0.70 | KDM4E (0.69) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL17280086 | 0.69 | MAPT (0.60) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL4053211 | 0.69 | AURKA (0.62) | KDM4EKMT2AALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |