Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | COMT | P21964 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | MMP13 | P45452 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302708 | 0.84 | COMT (0.56) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2244254 | 0.83 | KDM4E (1.00) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL179157 | 0.81 | NPC1 (0.63) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9043285 | 0.80 | KDM4E (0.61) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12010985 | 0.78 | COMT (0.83) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9041717 | 0.78 | STK33 (0.47) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2740044 | 0.78 | COMT (0.75) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29349700 | 0.78 | ALDH1A1 (0.72) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20982455 | 0.78 | ALDH1A1 (0.67) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2324292 | 0.77 | NPC1 (0.78) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |