Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042618 | 0.89 | MAPT (0.57) | MAOBFAAHNR4A2PARP10LMNA | |
| SCHEMBL9044252 | 0.86 | FFAR1 (0.58) | FFAR1PPARGMAPTSMN1; SMN2S1PR1 | |
| SCHEMBL9042419 | 0.85 | PTPRC (0.58) | MAOBNR4A2LTA4HFFAR1PARP10 | |
| SCHEMBL9040101 | 0.82 | PLA2G4B (0.60) | FFAR1MAPTSMN1; SMN2S1PR1S1PR3 | |
| SCHEMBL9043347 | 0.82 | FFAR1 (0.57) | FFAR1PPARGMAPTSMN1; SMN2 | |
| SCHEMBL9041763 | 0.81 | MAPT (0.67) | PARP10LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9041562 | 0.81 | PPARG (0.50) | FFAR1PPARGMAPTS1PR1S1PR3 | |
| SCHEMBL14966315 | 0.80 | MAPT (0.68) | MAOBNR4A2PARP10MAPTSMN1; SMN2 | |
| SCHEMBL9043998 | 0.80 | LMNA (0.53) | FFAR1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL836180 | 0.79 | CES2 (0.62) | LMNAALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |