Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040101 | 0.96 | PLA2G4B (0.60) | FFAR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9043347 | 0.93 | FFAR1 (0.57) | FFAR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9042678 | 0.88 | MAPT (0.64) | RAB9APLA2G4BMAPT | |
| SCHEMBL9044525 | 0.88 | MAPT (0.64) | RAB9APLA2G4BMAPTPPARG | |
| SCHEMBL9044226 | 0.87 | MAPT (0.62) | RAB9APLA2G4BMAPT | |
| SCHEMBL9043707 | 0.87 | MAPT (0.62) | RAB9APLA2G4BMAPT | |
| SCHEMBL9119262 | 0.87 | MEN1 (0.47) | FFAR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9044510 | 0.86 | MAPT (0.71) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL9044236 | 0.86 | MAOB (0.49) | FFAR1S1PR1S1PR3MAPTSMN1; SMN2 | |
| SCHEMBL9041562 | 0.85 | PPARG (0.50) | FFAR1RAB9ANPC1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |