Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044252 | 0.87 | FFAR1 (0.58) | MEN1KMT2ARAB9ANPC1PLA2G4B | |
| SCHEMBL9040101 | 0.85 | PLA2G4B (0.60) | MEN1KMT2ARAB9ANPC1PLA2G4B | |
| SCHEMBL9119572 | 0.83 | FFAR1 (0.46) | MEN1KMT2ARAB9ANPC1FFAR1 | |
| SCHEMBL9122892 | 0.83 | FFAR1 (0.55) | FFAR1S1PR1 | |
| SCHEMBL9043347 | 0.83 | FFAR1 (0.57) | MEN1KMT2ARAB9ANPC1PLA2G4B | |
| SCHEMBL9044525 | 0.81 | MAPT (0.64) | RAB9APLA2G4BHDAC1MAPT | |
| SCHEMBL9042575 | 0.81 | HDAC1 (0.51) | MEN1KMT2ARAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL9121262 | 0.81 | MLYCD (0.50) | MEN1KMT2ARAB9ANPC1PLA2G4B | |
| SCHEMBL9118461 | 0.80 | FFAR1 (0.72) | FFAR1S1PR1 | |
| SCHEMBL9119260 | 0.79 | RAB9A (0.45) | MEN1KMT2ARAB9ANPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453443-A | Antiallergens, antiinflammatory | MERCK FROSST CANADA, INC. (CA) | 1995-09-26 | — | — | US | disclosed |