SCHEMBL9044367

SCHEMBL9044367

CCN(CC)OC(=O)c1ncccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 1/20 0.44
FTO Q9C0B1 1/20 0.44
BRD4 O60885 1/20 0.40
TLR7 Q9NYK1 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 4/20 0.38
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
GRM4 Q14833 2/20 0.36
SPR P35270 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9316147 0.82 L3MBTL1 (0.45) EGLN2FTOBRD4TLR7L3MBTL1
SCHEMBL29396522 0.79 BRD4 (0.61) EGLN2FTOBRD4KDM4EMAPT
SCHEMBL1240286 0.79 BRD4 (0.61) EGLN2FTOBRD4KDM4EMAPT
SCHEMBL108876 0.76 L3MBTL1 (0.62) EGLN2FTOBRD4TLR7L3MBTL1
SCHEMBL8872750 0.76 EGLN2 (0.47) EGLN2FTOTLR7L3MBTL1MAPT
Hydrochloric Acid SCHEMBL6569637 0.75 L3MBTL1 (0.60) EGLN2FTOBRD4TLR7L3MBTL1
SCHEMBL27832422 0.74 EGLN2 (0.49) EGLN2FTOBRD4TLR7L3MBTL1
SCHEMBL30631986 0.74 EGLN2 (0.46) EGLN2FTOTLR7L3MBTL1KDM4E
SCHEMBL1302730 0.73 TSHR (0.56) L3MBTL1KDM4EMAPTCA12CA1
SCHEMBL3422060 0.73 EGLN2 (0.47) EGLN2FTOBRD4TLR7L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700907-A1 Process for producing pyrimidine derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-13 EP disclosed