Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | SI | P14410 | 1/20 | 0.71 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CBFB | Q13951 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564392 | 0.90 | MGAM (0.64) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL6511414 | 0.83 | MGAM (1.00) | MGAMGAASIMGAM2CBFB | |
| SCHEMBL9044504 | 0.80 | GUSB (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7718410 | 0.79 | MGAM (0.69) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL28425038 | 0.79 | TNKS (0.72) | GAAPARP1ALDH1A1TP53CYP3A4 | |
| SCHEMBL7719023 | 0.79 | MGAM (0.69) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL1170818 | 0.78 | CBFB (0.69) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL9045167 | 0.78 | PARP1 (0.60) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL7129510 | 0.77 | PKN1 (0.53) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL29412040 | 0.77 | PARP1 (0.66) | MGAMGAASIMGAM2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |