SCHEMBL9044675

SCHEMBL9044675

CCOC(=O)ON1CC2NCCC2C1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344735 0.78 GAA (0.33) ALDH1A1
SCHEMBL9040147 0.71 ALDH1A1 (0.34) ALDH1A1SOAT1
SCHEMBL31053634 0.66
SCHEMBL28970364 0.66
SCHEMBL14877493 0.65
SCHEMBL24104985 0.63 CHRM2 (0.36)
SCHEMBL24105176 0.63 CHRM2 (0.36)
SCHEMBL2409560 0.63 CHRM1 (0.42) ALDH1A1
SCHEMBL26945529 0.63 MAPT (0.35) ALDH1A1
SCHEMBL10434737 0.63 L3MBTL1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481274-B1 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives BAYER AG (DE) 1996-10-23 EP disclosed
EP-0393424-B1 Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes BAYER AG (DE) 1995-09-27 EP disclosed
EP-0481274-A1 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives BAYER AG (DE) 1992-04-22 EP disclosed
EP-0393424-A2 Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes BAYER AG (DE) 1990-10-24 EP disclosed