Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044907 | 0.87 | MAPT (0.46) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL9043235 | 0.87 | CTRC (0.48) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL8321070 | 0.80 | MAPT (0.70) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL9044361 | 0.79 | MAPT (0.40) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL9047684 | 0.79 | MAPT (0.50) | MAPTAPPSNCACTRCRAF1 | |
| Hydrochloric Acid SCHEMBL8318774 | 0.78 | MAPT (0.68) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL8320247 | 0.74 | MAPT (0.65) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL18822112 | 0.72 | MAPT (0.59) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL9047847 | 0.72 | APP (0.38) | MAPTAPPSNCACTRCRAF1 | |
| SCHEMBL8324356 | 0.71 | MAPT (0.65) | MAPTAPPSNCACTRCRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741726-A1 | SUBSTITUTED 3-ARYLIDENE-7-AZAOXINDOLE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-11-13 | — | — | EP | disclosed |