Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318368 | 0.83 | RAF1 (0.46) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL8321195 | 0.76 | RAF1 (0.47) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL9043235 | 0.72 | CTRC (0.48) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL9044710 | 0.72 | MAPT (0.46) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL9044907 | 0.72 | MAPT (0.46) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL8324445 | 0.72 | RAF1 (0.47) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL9047231 | 0.71 | KDM4E (0.49) | MAPTCTRCRAF1NTRK1SMN1; SMN2 | |
| SCHEMBL8318608 | 0.70 | RAF1 (0.43) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL8319991 | 0.69 | RAF1 (0.48) | APPMAPTSNCACTRCRAF1 | |
| SCHEMBL8320714 | 0.68 | MAPT (0.62) | APPMAPTSNCACTRCRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741726-A1 | SUBSTITUTED 3-ARYLIDENE-7-AZAOXINDOLE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-11-13 | — | — | EP | disclosed |