Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043709 | 0.82 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL9694466 | 0.82 | FFAR1 (0.39) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9043196 | 0.82 | FFAR1 (0.39) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9043138 | 0.80 | FFAR1 (0.38) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9044928 | 0.76 | ALDH1A1 (0.44) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9044002 | 0.75 | POLB (0.36) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9046268 | 0.74 | MEN1 (0.36) | FFAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9043406 | 0.73 | POLB (0.35) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8987703 | 0.71 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL12844485 | 0.70 | MAPT (0.62) | FFAR1POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | claimed |
| US-5175293-A | Substituted 2-aminopyrimidine derivatives | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |