Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043102 | 0.86 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9043138 | 0.85 | FFAR1 (0.38) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9043196 | 0.77 | FFAR1 (0.39) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9694466 | 0.77 | FFAR1 (0.39) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9044724 | 0.76 | FFAR1 (0.39) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9044002 | 0.72 | POLB (0.36) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9045354 | 0.71 | MEN1 (0.40) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9043694 | 0.70 | FFAR1 (0.38) | ALDH1A1MEN1KMT2AFFAR1SMN1; SMN2 | |
| SCHEMBL9046268 | 0.69 | MEN1 (0.36) | ALDH1A1L3MBTL1BLMMAPTMEN1 | |
| SCHEMBL9505703 | 0.68 | TAAR1 (0.54) | ALDH1A1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | claimed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | claimed |
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| US-5175293-A | Substituted 2-aminopyrimidine derivatives | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | disclosed |