Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045620 | 0.86 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL9044711 | 0.85 | ALDH1A1 (0.34) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9046268 | 0.85 | MEN1 (0.36) | POLBFFAR1ALDH1A1L3MBTL1BLM | |
| SCHEMBL9045189 | 0.80 | ALDH1A1 (0.33) | POLBALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL9694466 | 0.76 | FFAR1 (0.39) | POLBFFAR1ALDH1A1L3MBTL1BLM | |
| SCHEMBL9043196 | 0.76 | FFAR1 (0.39) | POLBFFAR1ALDH1A1L3MBTL1BLM | |
| SCHEMBL9044724 | 0.75 | FFAR1 (0.39) | POLBFFAR1ALDH1A1L3MBTL1BLM | |
| SCHEMBL9874096 | 0.74 | MEN1 (0.34) | POLBFFAR1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9043138 | 0.74 | FFAR1 (0.38) | POLBFFAR1ALDH1A1L3MBTL1BLM | |
| SCHEMBL9044928 | 0.72 | ALDH1A1 (0.44) | POLBFFAR1ALDH1A1L3MBTL1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | claimed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | claimed |
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | disclosed |