Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046220 | 0.87 | ACHE (1.00) | ACHEHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL10084674 | 0.84 | HPGD (0.53) | ACHEHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL9046728 | 0.82 | ACHE (1.00) | ACHEHSD17B10KDM4EHPGDHTT | |
| SCHEMBL9046826 | 0.81 | ACHE (0.87) | ACHEHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL9261167 | 0.80 | ACHE (0.56) | ACHEHSD17B10HPGDALDH1A1 | |
| SCHEMBL10085009 | 0.80 | KDM4E (0.68) | KDM4EHPGDHTTALDH1A1KMT2A | |
| SCHEMBL9411391 | 0.76 | ACHE (0.58) | ACHEALDH1A1MAOB | |
| SCHEMBL10085640 | 0.75 | HTR1D (0.51) | ACHEHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL9411647 | 0.74 | ACHE (0.53) | ACHEKMT2AMAOB | |
| SCHEMBL10085041 | 0.74 | KDM4E (0.51) | HSD17B10KDM4EHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |