Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046220 | 0.93 | ACHE (1.00) | ACHEHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL9046728 | 0.82 | ACHE (1.00) | ACHEHSD17B10HPGDKDM4EMAPK1 | |
| SCHEMBL9044733 | 0.81 | ACHE (0.77) | ACHEHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL3954335 | 0.78 | OPRM1 (0.73) | ACHEALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9044087 | 0.77 | ACHE (0.71) | ACHEHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL15613216 | 0.75 | MPO (0.77) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30877025 | 0.75 | HPGD (1.00) | ACHEHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL6982894 | 0.75 | HPGD (1.00) | ACHEHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL3107807 | 0.75 | CCR3 (0.71) | ACHEALDH1A1 | |
| SCHEMBL13904311 | 0.74 | ACHE (0.61) | ACHEHSD17B10ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |