Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046220 | 0.88 | ACHE (1.00) | ACHEKDM4EHPGDHSD17B10 | |
| SCHEMBL9044733 | 0.82 | ACHE (0.77) | ACHEKDM4EHPGDHSD17B10HTT | |
| SCHEMBL9046826 | 0.82 | ACHE (0.87) | ACHEKDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL24031218 | 0.78 | ACHE (0.64) | ACHEKDM4EHPGDGAAHSD17B10 | |
| SCHEMBL9411276 | 0.74 | ACHE (0.58) | ACHEKDM4EGAAHSD17B10HTT | |
| SCHEMBL9259946 | 0.73 | ACHE (0.58) | ACHE | |
| SCHEMBL9631092 | 0.73 | CA9 (0.59) | ACHEKDM4EHPGDGAATSHR | |
| SCHEMBL17241716 | 0.73 | CA9 (0.59) | ACHEKDM4EHPGDHTTRXFP1 | |
| SCHEMBL6161133 | 0.73 | CHRM1 (0.92) | CHRM1USP2MAPK1 | |
| SCHEMBL9044087 | 0.72 | ACHE (0.71) | ACHEKDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0742216-A2 | Cyclic amide derivatives | Eisai Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |