Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764920 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1RAB9A | |
| SCHEMBL11109283 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAL3MBTL1MAPK1RAB9A | |
| SCHEMBL12611640 | 0.78 | MAOB (0.45) | ALDH1A1MAPTMAPK1RAB9AHTT | |
| SCHEMBL11058642 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1RAB9A | |
| SCHEMBL6141237 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1555636 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL11117077 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL9117739 | 0.75 | RAB9A (0.51) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL9976430 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL9728624 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360258-B1 | Amino acid quinoline and naphthyridine derivatives | ABBOTT LAB (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0138416-B1 | GROWTH HORMONE RELEASE FACTOR ANALOGS | ELI LILLY AND COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5137872-A | Administering to animals | PITMAN-MOORE, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-5057520-A | Water solubility | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| US-5057523-A | Water soluble bactericide | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| US-RE33699-E | Polypeptides having norleucine, asparagine and aspartic acid groups to stimulate the release of Growth Hormone | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1991-09-24 | — | — | US | disclosed |
| US-4801456-A | Growth hormone-releasing factor analogs | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1989-01-31 | — | — | US | disclosed |
| US-4617149-A | ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0138416-A2 | Growth hormone release factor analogs | ELI LILLY AND COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| US-4415493-A | POTENTIATION; STIMULANTS; POLYPEPTIDES; ANTICARCINOGENIC AGENTS | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1983-11-15 | — | — | US | disclosed |
| EP-0022621-A1 | Peptides related to somatostatin, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-01-21 | — | — | EP | disclosed |
| EP-0011366-A2 | Synthetic peptides, their preparation, pharmaceutical formulations containing them and intermediates for their preparation | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4202802-A | PREFERENTIAL INHIBITION OF SCRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4199500-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4199501-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |