Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048247 | 0.87 | GPR52 (0.40) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9047365 | 0.84 | TSHR (0.46) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9044047 | 0.84 | CLCN2 (0.43) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9046010 | 0.84 | ALB (0.45) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9046705 | 0.82 | GABRA1 (0.41) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9045319 | 0.82 | GPR52 (0.46) | HPGDALDH1A1HSD17B10KDM4EGPR52 | |
| SCHEMBL6859420 | 0.81 | KDM4E (0.52) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL11858599 | 0.81 | ALDH1A1 (0.47) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL26679418 | 0.80 | HSD17B10 (0.50) | MYCHPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL9045316 | 0.80 | HPGD (0.50) | MYCHPGDALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |