SCHEMBL11808587

SCHEMBL11808587

CC(C)c1nnc(-c2ccccc2)c(=O)n1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 4/20 0.51
ADORA2B P29275 3/20 0.51
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 4/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPK14 Q16539 1/20 0.40
KDM5B Q9UGL1 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
TDP2 O95551 1/20 0.39
RAF1 P04049 1/20 0.39
MAP2K1 Q02750 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
GLA P06280 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064095 0.76 ADORA1 (0.54) ADORA1ADORA2BALDH1A1KDM4EGAA
SCHEMBL14425750 0.75 HSD11B1 (0.50) ALDH1A1TSHRKMT2A
SCHEMBL9843278 0.73 ADORA1 (0.51) ADORA1ADORA2BALDH1A1KDM4EGAA
SCHEMBL11813567 0.73 ADORA2B (0.51) ADORA1ADORA2BALDH1A1KDM4EGAA
SCHEMBL9045010 0.71 KDM5A (0.47) ADORA1ADORA2BALDH1A1KDM4EGAA
SCHEMBL23105448 0.69 CNR1 (0.48) ALDH1A1KDM4EGAAHPGDHSD17B10
SCHEMBL15135212 0.69 ALDH1A1 (0.58) ADORA1ADORA2BALDH1A1KDM4EGAA
SCHEMBL6979700 0.68 KDM4E (0.60) ALDH1A1KDM4ECYP1A2CYP2C19CYP2C9
SCHEMBL14953694 0.68 CNR1 (0.41) ALDH1A1KDM4EGAAHPGDCYP1A2
SCHEMBL11717418 0.66 POLB (0.56) ADORA1ADORA2BALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3940391-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-02-24 US disclosed